Task management shouldn’t be your full time job. We’ve built OmniFocus to take a load off your mind by managing your tasks the way that you want, freeing you to focus your attention on the things that matter to you most. Finish that novel. Spend more time with your friends and family. Grow your business. Let us worry about keeping your goals and tasks, both personal and professional, in one ordered, easy to access system that you can depend on.
I've been waiting on this app for a while (and apparently I'm not the only one). For the past few months, I've been using Vitalist without issue, and really like being able to access/edit it from anywhere (it's web-based), but a "local" solution could probably work just as well, using a combination of Back to My Mac and the rumored ultra-portable.