If you haven't yet read DrunkenBlog's interview with Brent and Sheila Simmons (of NetNewsWire fame), you're really missing out. It's an interesting peek into the world of an independent (and successful) software developer. My favorite excerpt from the interview is when Brent is explaining how working together with Sheila at home every day isn't so bad.
It's a little bit like farm life — but modern, urban, digital farm life. We grow software.